International Society for the Development of Research on Magnesium

updated March 30, 2013

Scientific Committee


President


Prof. Federica I. Wolf

Rome (Italy)



"Dear Colleagues and Friends,...

SDRM_memberLetter



Past Presidents


Dr. Jean Durlach

Paris (France)

(Honorary President)


Dr. Yves Rayssiguier

Clermont-Ferrand (France)


Dr. André Mazur

Clermont-Ferrand (France)




Society Board


Stefano Iotti

Bologna (Italy)


Maria-José Laires

Lisbon (Portugal)


André Mazur

Clermont-Ferrand (France)

(Vice-President)


Nicole Pages

Paris/Strasbourg (France)


Yves Rayssiguier

Clermont-Ferrand (France)


Edmond Rock

Clermont-Ferrand (France)

(Secretary/Treasurer)



HOME | Highlights




The SLC41 family of MgtE-like magnesium transporters.

Sahni J, Scharenberg AM. (PLoS One. 2013 Apr;34(2-3):620-8.)

 

Baseline serum magnesium concentrations and neurodevelopmental outcomes of extremely low birth weight premature infants.

Kim SY, El-Dib M, Ahmad T, Aly H. (Early Hum Dev. 2013 Apr;89(4):239-42.)

 

Higher Magnesium Intake Is Associated with Lower Fasting Glucose and Insulin, with No Evidence of Interaction with Select Genetic Loci, in a Meta-Analysis of 15 CHARGE Consortium Studies.

Hruby A, Ngwa JS, Renström F, et al. (J Nutr. 2013 Mar;143(3):345-53.)

 

Sphingosine and FTY720 are potent inhibitors of the transient receptor potential melastatin 7 (TRPM7) channels.

Qin X, Yue Z, Sun B, et al. (Br J Pharmacol. 2013 Mar;168(6):1294-312.)

 

Magnesium sulphate for women at term for neuroprotection of the fetus.

Nguyen TM, Crowther CA, Wilkinson D, Bain E. (Cochrane Database Syst Rev. 2013 Feb 28.)

 

Magnesium Supplementation Reduces Postoperative Arrhythmias After Cardiopulmonary Bypass in Pediatrics: A Metaanalysis of Randomized Controlled Trials.

Lee HY, Ghimire S, Kim EY. (Pediatr Cardiol. 2013 Feb 27.)

 

Safety and efficacy of calcium and magnesium infusions in the chemoprevention of oxaliplatin induced sensory neuropathy in digestive tract cancers: A meta-analysis.

Xu XT, Dai ZH, Xu Q, et al. (J Dig Dis. 2013 Feb 21.)

 

Modifying effect of calcium/magnesium intake ratio and mortality: a population-based cohort study.

Dai Q, Shu XO, Deng X, et al (BMJ Open. 2013 Feb 20;3(2))

 

The TRPM6/EGF Pathway Is Downregulated in a Rat Model of Cisplatin Nephrotoxicity.

Ledeganck KJ, Boulet GA, Bogers JJ, et al (PLoS One 2013;8(2) Epub 2013 Feb 15.)

 

Associations of serum and urinary magnesium with the pre-diabetes, diabetes and diabetic complications in the chinese northeast population.

Xu J, Xu W, Yao H, et al. (PLoS One 2013;8(2), Epub 2013 Feb 13.)

 

TRPM7 mediates breast cancer cell migration and invasion through the MAPK pathway.

Meng X, Cai C, Wu J, et al (Cancer Lett. 2013 Jan 23. Epub ahead of print)

 

Increase in serum Ca2+/Mg2+ ratio promotes proliferation of prostate cancer cells by activating TRPM7 channels.

Sun Y, Selvaraj S, Varma A et al (J Biol Chem. 2013 Jan 4;288(1):255-63.)

 

Magnesium prevents phosphate-induced calcification in human aortic vascular smooth muscle cells.

Louvet L, Büchel J, Steppan S et al. (Nephrol Dial Transplant. 2012 Dec 9. Epub ahead of print)

 

Evaluation of Hypomagnesemia: Lessons From Disorders of Tubular Transport.

Dimke H, Monnens L, Hoenderop JG, Bindels RJ. (Am J Kidney Dis. 2012 Nov 29. doi:pii: S0272-6386(12)01345-5.)

 

Structural asymmetry in the magnesium channel CorA points to sequential allosteric regulation.

Pfoh R, Li A, Chakrabarti N, et al (Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):18809-14.)

 

Differential effects of cyclosporin A and tacrolimus on magnesium influx in Caco2 cells.

Gouadon E, Lecerf F, German-Fattal M. (J Pharm Pharm Sci.2012;15(3):389-98.)

 

The B. subtilis MgtE magnesium transporter can functionally compensate TRPM7-deficiency in vertebrate B-cells.

Sahni J, Song Y, Scharenberg AM. (Mol Aspects Med. 2012;7(9):e44452.)

 

Disorders of calcium and magnesium balance: a physiology-based approach.

Hoorn EJ, Zietse R. (Pediatr Nephrol. 2012 Nov 10. Epub ahead of print)

 

Evidence for functional expression of TRPM7 channels in human atrial myocytes.

Zhang YH, Sun HY, Chen KH, Du XL, Liu B, Cheng LC, Li X, Jin MW, Li GR. (Basic Res Cardiol. 2012 Sep;107(5):282.)

 

Oral magnesium lozenge reduces postoperative sore throat: a randomized, prospective, placebo-controlled study.

Borazan H, Kececioglu A, Okesli S, Otelcioglu S. (Anesthesiology. 2012 Sep;117(3):512-8.)

 

Coupled gating of skeletal muscle ryanodine receptors is modulated by Ca2+, Mg2+, and ATP.

Porta M, Diaz-Sylvester PL, Neumann JT, Escobar AL, Fleischer S, Copello JA. (Am J Physiol Cell Physiol. 2012 Sep 15;303(6):C682-97.)

 

IRBIT reduces the apparent affinity for intracellular Mg˛ in inhibition of the electrogenic Na-HCO cotransporter NBCe1-B.

Yamaguchi S, Ishikawa T. (Biochem Biophys Res Commun. 2012 Aug 3;424(3):433-8.)

 

Loss of insulin-induced activation of TRPM6 magnesium channels results in impaired glucose tolerance during pregnancy.

Nair AV, Hocher B, Verkaart S, van Zeeland F, Pfab T, Slowinski T, Chen YP, Schlingmann KP, Schaller A, Gallati S, Bindels RJ, Konrad M, Hoenderop JG. (Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11324-9.)

 

The periplasmic loop provides stability to the open state of the CorA magnesium channel.

Palombo I, Daley DO, Rapp M. (J Biol Chem. 2012 Aug 10;287(33):27547-55.)

 

Ion channels and transporters in lymphocyte function and immunity.

Feske S, Skolnik EY, Prakriya M. (Nat Rev Immunol. 2012 Jun 15;12(7):532-47.)

 

Magnesium and its transporters in cancer: a novel paradigm in tumour development.

Wolf FI, Trapani V. (Clin Sci (Lond). 2012 Oct;123(7):417-27.)

 

TRPM7: a unique channel involved in magnesium homeostasis.

Paravicini TM, Chubanov V, Gudermann T. (Int J Biochem Cell Biol. 2012 Aug;44(8):1381-4.)

 

Mg(2+) block of Drosophila NMDA receptors is required for long-term memory formation and CREB-dependent gene expression.

Miyashita T, Oda Y, Horiuchi J, Yin JC, Morimoto T, Saitoe M. (Neuron. 2012 Jun 7;74(5):887-98.)

 

Regulation of the ATPase activity of ABCE1 from Pyrococcus abyssi by Fe-S cluster status and Mg˛: implication for ribosomal function.

Sims LM, Igarashi RY. (Arch Biochem Biophys. 2012 Aug 15;524(2):114-22.)

 

NMDA receptors with incomplete Mg˛ block enable low-frequency transmission through the cerebellar cortex.

Schwartz EJ, Rothman JS, Dugué GP, Diana M, Rousseau C, Silver RA, Dieudonné S. (J Neurosci. 2012 May 16;32(20):6878-93.)

 

Magnesium and calcium deficiencies additively increase zinc concentrations and metallothionein expression in the rat liver.

Kotani M, Kim KH, Ishizaki N, Funaba M, Matsui T. (Br J Nutr. 2012 May 9:1-8. Epub ahead of print)

 

Functional reconstitution and characterization of the Arabidopsis Mg(2+) transporter AtMRS2-10 in proteoliposomes.

Ishijima S, Shigemi Z, Adachi H, Makinouchi N, Sagami I. (Biochim Biophys Acta. 2012 Sep;1818(9):2202-8.)

 

Tungstate activates BK channels in a ß subunit- and Mg2+-dependent manner: relevance for arterial vasodilatation.

Fernández-Marińo AI, Porras-González C, González-Rodríguez P, Selent J, Pastor M, Ureńa J, Castellano A, Valverde MA, Fernández-Fernández JM. (Cardiovasc Res. 2012 Jul 1;95(1):29-38)

 

Sensitivity of TRPM7 channels to Mg2+ characterized in cell-free patches of Jurkat T lymphocytes.

Chokshi R, Matsushita M, Kozak JA. (Am J Physiol Cell Physiol. 2012 Jun 1;302(11):C1642-51.)

 

Magnesium sulfate suppresses L-type calcium currents on the basilar artery smooth muscle cells in rabbits.

Sharma N, Cho DH, Kim SY, Bhattarai JP, Hwang PH, Han SK. (Neurol Res. 2012 Apr;34(3):291-6.)

 

Differential expression of TRPM7 in rat hepatoma and embryonic and adult hepatocytes.

Lam DH, Grant CE, Hill CE. (Can J Physiol Pharmacol. 2012 Apr;90(4):435-44.)

 

Is ryanodine receptor a calcium or magnesium channel? Roles of K+ and Mg2+ during Ca2+ release.

Gillespie D, Chen H, Fill M. (Cell Calcium. 2012 Jun;51(6):427-33.)

 

Detailed examination of Mg2+ and pH sensitivity of human TRPM7 channels.

Chokshi R, Matsushita M, Kozak JA. (Am J Physiol Cell Physiol. 2012 Apr 1;302(7):C1004-11.)

 

Mechanisms of Mg2+ inhibition of BzATP-dependent Ca2+ responses in THP-1 monocytes.

Jantaratnotai N, McGeer PL, McLarnon JG. (Brain Res. 2012 Mar 9;1442:1-8.)

 

Influence of external magnesium ions on the NMDA receptor channel block by different types of organic cations.

Nikolaev MV, Magazanik LG, Tikhonov DB. (Neuropharmacology. 2012 Apr;62(5-6):2078-85.)

 

Mitochondrial ATP synthase catalytic mechanism: a novel visual comparative structural approach emphasizes pivotal roles for Mg˛ and P-loop residues in making ATP.

Blum DJ, Ko YH, Pedersen PL. (Biochemistry. 2012 Feb 21;51(7):1532-46.)

 

Drug-induced alterations in Mg2+ homoeostasis.

Lameris AL, Monnens LA, Bindels RJ, Hoenderop JG. (Clin Sci (Lond). 2012 Jul;123(1):1-14.)

 

Natural and synthetic modulators of SK (K(ca) 2) potassium channels inhibit magnesium-dependent activity of the kinase-coupled cation channel TRPM7.

Chubanov V, Mederos Y Schnitzler M, Meißner M, Schäfer S, Abstiens K, Hofmann T, Gudermann T. (Br J Pharmacol. 2012 Jun;166(4):1357-76. doi: 10.1111/j.1476-5381.2012.01855.x.

 

Magnesium Decreases Inflammatory Cytokine Production: A Novel Innate Immunomodulatory Mechanism.

Sugimoto J, Romani AM, Valentin-Torres AM, Luciano AA, Ramirez Kitchen CM, Funderburg N, Mesiano S, Bernstein HB. (J Immunol. 2012 May 18. Epub ahead of print)

 

A Key Role for Mg2+ in TRPM7's Control of ROS Levels During Cell Stress.

Chen HC, Su LT, González-Pagán O, Overton JD, Runnels LW. (Biochem J. 2012 May 15. Epub ahead of print)

 

Magnesium sulfate reduces bacterial LPS-induced inflammation at the maternal-fetal interface.

Dowling O, Chatterjee PK, Gupta M, Tam Tam HB, Xue X, Lewis D, Rochelson B, Metz CN. (Placenta. 2012 May;33(5):392-8. Epub 2012 Feb 16.)

 

Hypoxia Disruption of Vertebrate CNS Pathfinding through EphrinB2 Is Rescued by Magnesium.

Stevenson TJ, Trinh T, Kogelschatz C, Fujimoto E, Lush ME, Piotrowski T, Brimley CJ, Bonkowsky JL. (PLoS Genet. 2012 Apr;8(4):e1002638. Epub 2012 Apr 12.)

 

Associations of dietary magnesium intake with mortality from cardiovascular disease: the JACC study.

Zhang W, Iso H, Ohira T, Date C, Tamakoshi A; JACC Study Group. (Atherosclerosis. 2012 Apr;221(2):587-95. Epub 2012 Jan 28.)

 

Magnesium intake, plasma C-peptide, and colorectal cancer incidence in US women: a 28-year follow-up study.

Zhang X, Giovannucci EL, Wu K, Smith-Warner SA, Fuchs CS, Pollak M, Willett WC, Ma J (Br J Cancer. 2012 Mar 27;106(7):1335-41. doi: 10.1038/bjc.2012.76. Epub 2012 Mar 13.)

 

Transient receptor potential melastatin-related 7 channel is overexpressed in human pancreatic ductal adenocarcinomas and regulates human pancreatic cancer cell migration.

Rybarczyk P, Gautier M, Hague F, Dhennin-Duthille I, Chatelain D, Kerr-Conte J, Pattou F, Regimbeau JM, Sevestre H, Ouadid-Ahidouch H. (Int J Cancer. 2012 Feb 10. doi: 10.1002/ijc.27487. Epub ahead of print)

 

Magnesium – a versatile and often overlooked element: new perspectives with a focus on chronic kidney disease.

(Clinical Kidney Journal, Volume 5 Suppl 1 February 2012)

 

Diabetes is the main factor accounting for hypomagnesemia in obese subjects.

Lecube A, Baena-Fustegueras JA, Fort JM, Pelegrí D, Hernández C, Simó R. (PLoS One. 2012;7(1):e30599. Epub 2012 Jan 24.)

 

The channel kinase, TRPM7, is required for early embryonic development.

Jin J, Wu LJ, Jun J, Cheng X, Xu H, Andrews NC, Clapham DE. (Proc Natl Acad Sci USA. 2012 Jan 31;109(5):E225-33. Epub 2011 Dec 27.)

 

Silencing TRPM7 mimics the effects of magnesium deficiency in human microvascular endothelial cells.

Baldoli E, Maier JA. (Angiogenesis. , 2011 Dec 20. Epub ahead of print)

 

Nitric oxide mediates low magnesium inhibition of osteoblast-like cell proliferation.

Leidi M, et al. (J Nutr Biochem. , 2011 Dec 29. Epub ahead of print)

 

Diaza-18-crown-6 hydroxyquinoline derivatives as flexible tools for the assessment and imaging of total intracellular magnesium.

Marraccini C, et al. (Chem. Sci. , 2011, In press (DOI:10.1039/C1SC00751C)

 

Intracellular concentration map of magnesium in whole cells by combined use of  x-ray fluorescence microscopy and atomic force microscopy.

Lagomarsino S, et al. (Spectrochimica Acta B , 2011, In press (DOI:10.1016/j.sab.2011.11.002).

 

Effects of elevation of brain magnesium on fear conditioning, fear extinction, and synaptic plasticity in the infralimbic prefrontal cortex and lateral amygdala.

Abumaria N et al. (J Neurosci. , 2011 Oct 19;31(42):14871-81).

 

The human gene SLC41A1 encodes for the Na+/Mg2+ exchanger.

Kolisek M, Nestler A, Vormann J, Schweigel-Röntgen M. (Am J Physiol Cell Physiol. , 2011 Oct 26. Epub ahead of print)

 

Short-term magnesium deficiency upregulates ceramide synthase in cardiovascular tissues and cells: cross-talk between cytokines, Mg2+,NF-kB and de novo ceramide

Altura BM, Shah NC, Shah G, Zhang A, Li W, Zheng T, Perez-Albela JL, Altura BT (Am J Physiol Heart Circ Physiol., 2011 Oct 7. Epub ahead of print)

 

Waixenicin A inhibits cell proliferation through magnesium-dependent block of TRPM7

Zierler S, Yao G, Zhang Z, Kuo WC, Poerzgen P, Penner R, Horgen FD, Fleig A (J Biol Chem., 2011 Sep 16. Epub ahead of print)

 

Hydroxyapatite coating on magnesium with MgF(2) interlayer for enhanced corrosion resistance and biocompatibility

Jo JH, Kang BG, Shin KS, Kim HE, Hahn BD, Park DS, Koh YH (J Mater Sci Mater Med. 2011 Sep 10. Epub ahead of print)

 

Newly developed Mg-selective fluorescent probe enables visualization of Mg dynamics in mitochondria

Shindo Y, Fujii T, Komatsu H, Citterio D, Hotta K, Suzuki K, Oka K. (PLoS One., 2011;6(8):e23684. Epub 2011 Aug 16)

 

Cardiovascular and intestinal responses to oxidative and nitrosative stress during prolonged magnesium deficiency

Weglicki WB, Chmielinska JJ, Kramer JH, Mak IT. (Am J Med Sci., 2011 Aug;342(2):125-8)

 

Second messenger role for Mg2+ revealed by human T-cell immunodeficiency

Feng-Yen Li, Benjamin Chaigne-Delalande, Chrysi Kanellopoulou, Jeremiah C. Davis, Helen F. Matthews, Daniel C. Douek, Jeffrey I. Cohen, Gulbu Uzel, Helen C. Su, Michael J. Lenardo (Nature, 475:471–476, Epub 27 July 2011)

 

Dysregulation of renal transient receptor potential melastatin 6/7 but not paracellin-1 in aldosterone-induced hypertension and kidney damage in a model of hereditary hypomagnesemia

Yogi A, Callera GE, O'Connor SE, He Y, Correa JW, Tostes RC, Mazur A, Touyz RM. (J Hypertens., 2011 Jul;29(7):1400-10)

 

Magnesium deficiency suppresses cell cycle progression mediated by increase in transcriptional activity of p21(Cip1) and p27(Kip1) in renal epithelial NRK-52E cells.

Ikari A, Sawada H, Sanada A, Tonegawa C, Yamazaki Y, Sugatani J. (J Cell Biochem., 2011 Jul 21. doi: 10.1002/jcb.23284. Epub ahead of print)

 

The Mg2+ transporter MagT1 partially rescues cell growth and Mg2+ uptake in cells lacking the channel-kinase TRPM7

Deason-Towne F, Perraud AL, Schmitz C. (FEBS Lett. 2011 Jul 21;585(14):2275-8. Epub 2011 May 27)

 

Hypoxia induces an increase in intracellular magnesium via transient receptor potential melastatin 7 (TRPM7) channels in rat hippocampal neurons in vitro

Zhang J, Zhao F, Zhao Y, Wang J, Pei L, Sun N, Shi J. (J Biol Chem., 2011 Jun 10;286(23):20194-207. Epub 2011 Apr 12)

 

Blood magnesium, and the interaction with calcium, on the risk of high-grade prostate cancer.

Dai Q, Motley SS, Smith JA Jr, Concepcion R, Barocas D, Byerly S, Fowke JH. (PLoS One. 2011 Apr 25;6(4):e18237)

 

Changes in brain protein expression are linked to magnesium restriction-induced depression-like behavior

Whittle N, Li L, Chen WQ, Yang JW, Sartori SB, Lubec G, Singewald N. (Amino Acids. 2011 Apr;40(4):1231-48. Epub 2011 Feb 11)

 

 


Sponsors