International Society for the Development of Research on Magnesium

Scientific Committee


Prof. Federica I. Wolf

Rome (Italy)

"Dear Colleagues and Friends,...


Past Presidents

Dr. Jean Durlach

Paris (France)


Dr. André Mazur

Clermont-Ferrand (France)

Dr. Yves Rayssiguier

Clermont-Ferrand (France)

Society Board

Andrea Fleig

Honolulu (USA)

Thomas Gudermann

Munich (Germany)

Michael Lenardo

Bethesda (USA)

André Mazur

Clermont-Ferrand (France)


Yves Rayssiguier

Clermont-Ferrand (France)

Edmond Rock

Clermont-Ferrand (France)


HOME | Highlights


2011 | 2012 | 2013 | 2014 | 2015

Magnesium prevents phosphate-induced calcification in human aortic vascular smooth muscle cells.

Louvet L, Büchel J, Steppan S et al. (Nephrol Dial Transplant. 2012 Dec 9. Epub ahead of print)


Evaluation of Hypomagnesemia: Lessons From Disorders of Tubular Transport.

Dimke H, Monnens L, Hoenderop JG, Bindels RJ. (Am J Kidney Dis. 2012 Nov 29. doi:pii: S0272-6386(12)01345-5.)


Structural asymmetry in the magnesium channel CorA points to sequential allosteric regulation.

Pfoh R, Li A, Chakrabarti N, et al (Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):18809-14.)


Differential effects of cyclosporin A and tacrolimus on magnesium influx in Caco2 cells.

Gouadon E, Lecerf F, German-Fattal M. (J Pharm Pharm Sci.2012;15(3):389-98.)


The B. subtilis MgtE magnesium transporter can functionally compensate TRPM7-deficiency in vertebrate B-cells.

Sahni J, Song Y, Scharenberg AM. (Mol Aspects Med. 2012;7(9):e44452.)


Disorders of calcium and magnesium balance: a physiology-based approach.

Hoorn EJ, Zietse R. (Pediatr Nephrol. 2012 Nov 10. Epub ahead of print)


Evidence for functional expression of TRPM7 channels in human atrial myocytes.

Zhang YH, Sun HY, Chen KH, Du XL, Liu B, Cheng LC, Li X, Jin MW, Li GR. (Basic Res Cardiol. 2012 Sep;107(5):282.)


Oral magnesium lozenge reduces postoperative sore throat: a randomized, prospective, placebo-controlled study.

Borazan H, Kececioglu A, Okesli S, Otelcioglu S. (Anesthesiology. 2012 Sep;117(3):512-8.)


Coupled gating of skeletal muscle ryanodine receptors is modulated by Ca2+, Mg2+, and ATP.

Porta M, Diaz-Sylvester PL, Neumann JT, Escobar AL, Fleischer S, Copello JA. (Am J Physiol Cell Physiol. 2012 Sep 15;303(6):C682-97.)


IRBIT reduces the apparent affinity for intracellular Mg˛ in inhibition of the electrogenic Na-HCO cotransporter NBCe1-B.

Yamaguchi S, Ishikawa T. (Biochem Biophys Res Commun. 2012 Aug 3;424(3):433-8.)


Loss of insulin-induced activation of TRPM6 magnesium channels results in impaired glucose tolerance during pregnancy.

Nair AV, Hocher B, Verkaart S, van Zeeland F, Pfab T, Slowinski T, Chen YP, Schlingmann KP, Schaller A, Gallati S, Bindels RJ, Konrad M, Hoenderop JG. (Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11324-9.)


The periplasmic loop provides stability to the open state of the CorA magnesium channel.

Palombo I, Daley DO, Rapp M. (J Biol Chem. 2012 Aug 10;287(33):27547-55.)


Ion channels and transporters in lymphocyte function and immunity.

Feske S, Skolnik EY, Prakriya M. (Nat Rev Immunol. 2012 Jun 15;12(7):532-47.)


Magnesium and its transporters in cancer: a novel paradigm in tumour development.

Wolf FI, Trapani V. (Clin Sci (Lond). 2012 Oct;123(7):417-27.)


TRPM7: a unique channel involved in magnesium homeostasis.

Paravicini TM, Chubanov V, Gudermann T. (Int J Biochem Cell Biol. 2012 Aug;44(8):1381-4.)


Mg(2+) block of Drosophila NMDA receptors is required for long-term memory formation and CREB-dependent gene expression.

Miyashita T, Oda Y, Horiuchi J, Yin JC, Morimoto T, Saitoe M. (Neuron. 2012 Jun 7;74(5):887-98.)


Regulation of the ATPase activity of ABCE1 from Pyrococcus abyssi by Fe-S cluster status and Mg˛: implication for ribosomal function.

Sims LM, Igarashi RY. (Arch Biochem Biophys. 2012 Aug 15;524(2):114-22.)


NMDA receptors with incomplete Mg˛ block enable low-frequency transmission through the cerebellar cortex.

Schwartz EJ, Rothman JS, Dugué GP, Diana M, Rousseau C, Silver RA, Dieudonné S. (J Neurosci. 2012 May 16;32(20):6878-93.)


Magnesium and calcium deficiencies additively increase zinc concentrations and metallothionein expression in the rat liver.

Kotani M, Kim KH, Ishizaki N, Funaba M, Matsui T. (Br J Nutr. 2012 May 9:1-8. Epub ahead of print)


Functional reconstitution and characterization of the Arabidopsis Mg(2+) transporter AtMRS2-10 in proteoliposomes.

Ishijima S, Shigemi Z, Adachi H, Makinouchi N, Sagami I. (Biochim Biophys Acta. 2012 Sep;1818(9):2202-8.)


Tungstate activates BK channels in a ß subunit- and Mg2+-dependent manner: relevance for arterial vasodilatation.

Fernández-Marińo AI, Porras-González C, González-Rodríguez P, Selent J, Pastor M, Ureńa J, Castellano A, Valverde MA, Fernández-Fernández JM. (Cardiovasc Res. 2012 Jul 1;95(1):29-38)


Sensitivity of TRPM7 channels to Mg2+ characterized in cell-free patches of Jurkat T lymphocytes.

Chokshi R, Matsushita M, Kozak JA. (Am J Physiol Cell Physiol. 2012 Jun 1;302(11):C1642-51.)


Magnesium sulfate suppresses L-type calcium currents on the basilar artery smooth muscle cells in rabbits.

Sharma N, Cho DH, Kim SY, Bhattarai JP, Hwang PH, Han SK. (Neurol Res. 2012 Apr;34(3):291-6.)


Differential expression of TRPM7 in rat hepatoma and embryonic and adult hepatocytes.

Lam DH, Grant CE, Hill CE. (Can J Physiol Pharmacol. 2012 Apr;90(4):435-44.)


Is ryanodine receptor a calcium or magnesium channel? Roles of K+ and Mg2+ during Ca2+ release.

Gillespie D, Chen H, Fill M. (Cell Calcium. 2012 Jun;51(6):427-33.)


Detailed examination of Mg2+ and pH sensitivity of human TRPM7 channels.

Chokshi R, Matsushita M, Kozak JA. (Am J Physiol Cell Physiol. 2012 Apr 1;302(7):C1004-11.)


Mechanisms of Mg2+ inhibition of BzATP-dependent Ca2+ responses in THP-1 monocytes.

Jantaratnotai N, McGeer PL, McLarnon JG. (Brain Res. 2012 Mar 9;1442:1-8.)


Influence of external magnesium ions on the NMDA receptor channel block by different types of organic cations.

Nikolaev MV, Magazanik LG, Tikhonov DB. (Neuropharmacology. 2012 Apr;62(5-6):2078-85.)


Mitochondrial ATP synthase catalytic mechanism: a novel visual comparative structural approach emphasizes pivotal roles for Mg˛ and P-loop residues in making ATP.

Blum DJ, Ko YH, Pedersen PL. (Biochemistry. 2012 Feb 21;51(7):1532-46.)


Drug-induced alterations in Mg2+ homoeostasis.

Lameris AL, Monnens LA, Bindels RJ, Hoenderop JG. (Clin Sci (Lond). 2012 Jul;123(1):1-14.)


Natural and synthetic modulators of SK (K(ca) 2) potassium channels inhibit magnesium-dependent activity of the kinase-coupled cation channel TRPM7.

Chubanov V, Mederos Y Schnitzler M, Meißner M, Schäfer S, Abstiens K, Hofmann T, Gudermann T. (Br J Pharmacol. 2012 Jun;166(4):1357-76. doi: 10.1111/j.1476-5381.2012.01855.x.


Magnesium Decreases Inflammatory Cytokine Production: A Novel Innate Immunomodulatory Mechanism.

Sugimoto J, Romani AM, Valentin-Torres AM, Luciano AA, Ramirez Kitchen CM, Funderburg N, Mesiano S, Bernstein HB. (J Immunol. 2012 May 18. Epub ahead of print)


A Key Role for Mg2+ in TRPM7's Control of ROS Levels During Cell Stress.

Chen HC, Su LT, González-Pagán O, Overton JD, Runnels LW. (Biochem J. 2012 May 15. Epub ahead of print)


Magnesium sulfate reduces bacterial LPS-induced inflammation at the maternal-fetal interface.

Dowling O, Chatterjee PK, Gupta M, Tam Tam HB, Xue X, Lewis D, Rochelson B, Metz CN. (Placenta. 2012 May;33(5):392-8. Epub 2012 Feb 16.)


Hypoxia Disruption of Vertebrate CNS Pathfinding through EphrinB2 Is Rescued by Magnesium.

Stevenson TJ, Trinh T, Kogelschatz C, Fujimoto E, Lush ME, Piotrowski T, Brimley CJ, Bonkowsky JL. (PLoS Genet. 2012 Apr;8(4):e1002638. Epub 2012 Apr 12.)


Associations of dietary magnesium intake with mortality from cardiovascular disease: the JACC study.

Zhang W, Iso H, Ohira T, Date C, Tamakoshi A; JACC Study Group. (Atherosclerosis. 2012 Apr;221(2):587-95. Epub 2012 Jan 28.)


Magnesium intake, plasma C-peptide, and colorectal cancer incidence in US women: a 28-year follow-up study.

Zhang X, Giovannucci EL, Wu K, Smith-Warner SA, Fuchs CS, Pollak M, Willett WC, Ma J (Br J Cancer. 2012 Mar 27;106(7):1335-41. doi: 10.1038/bjc.2012.76. Epub 2012 Mar 13.)


Transient receptor potential melastatin-related 7 channel is overexpressed in human pancreatic ductal adenocarcinomas and regulates human pancreatic cancer cell migration.

Rybarczyk P, Gautier M, Hague F, Dhennin-Duthille I, Chatelain D, Kerr-Conte J, Pattou F, Regimbeau JM, Sevestre H, Ouadid-Ahidouch H. (Int J Cancer. 2012 Feb 10. doi: 10.1002/ijc.27487. Epub ahead of print)


Magnesium – a versatile and often overlooked element: new perspectives with a focus on chronic kidney disease.

(Clinical Kidney Journal, Volume 5 Suppl 1 February 2012)


Diabetes is the main factor accounting for hypomagnesemia in obese subjects.

Lecube A, Baena-Fustegueras JA, Fort JM, Pelegrí D, Hernández C, Simó R. (PLoS One. 2012;7(1):e30599. Epub 2012 Jan 24.)