ARCHIVES | 2011 – 2012 – 2013 – 2014 – 2015 2013 Elucidation of the distal convoluted tubule transcriptome identifies new candidate genes involved in renal Mg2+ handling de Baaij JH, Groot Koerkamp MJ, et al. (Am J Physiol Renal Physiol. 2013 Dec;305(11):F1563-73. doi: 10.1152/ajprenal.00322.2013.) Dietary magnesium and genetic interactions in diabetes and related risk factors: a brief overview of current knowledge Hruby A, McKeown NM, Song Y, Djoussé L. (Nutrients. 2013 Dec 6;5(12):4990-5011. doi: 10.3390/nu5124990.) Effect of magnesium supplementation and depletion on the onset and course of acute experimental pancreatitis Verena Schick, Jonas A Scheiber, Frank C Mooren (Gut 2013 Nov 25. doi: 10.1136/gutjnl-2012-304274. Epub ahead of print) Magnesium Intake Is Inversely Associated With Coronary Artery Calcification: The Framingham Heart Study Hruby A, O’Donnell CJ, Jacques PF, Meigs JB, Hoffmann U, McKeown NM. (JACC Cardiovasc Imaging. 2013 Nov 20. doi: 10.1016/j.jcmg.2013.10.006. Epub ahead of print) Transient receptor potential melastatin 7 is involved in oestrogen receptor-negative metastatic breast cancer cells migration through its kinase domain Guilbert A, Gautier M, Dhennin-Duthille I,et al. (Eur J Cancer. 2013 Nov;49(17):3694-707. doi: 10.1016/j.ejca.2013.07.008.) Importance of Metal Hydration on the Selectivity of Mg(2+) versus Ca(2+) in Magnesium Ion Channels Dudev T, Lim C. (J Am Chem Soc. 2013 Nov 13;135(45):17200-8. doi: 10.1021/ja4087769. Epub 2013 Oct 30.) TRPM7 triggers Ca2+sparks and invadosome formation inneuroblastoma cells Daan Visser, Michiel Langeslagb, Katarzyna M. et al. (Cell Calcium 2013) Mutations in PCBD1 Cause Hypomagnesemia and Renal Magnesium Wasting Ferrè S, de Baaij JH, Ferreira P, et al. (J Am Soc Nephrol. 2013 Nov 7. Epub ahead of print.) Aldosterone signaling through transient receptor potential melastatin 7 cation channel (TRPM7) and its a-kinase domain Yogi A, Callera GE, O’Connor S, Antunes TT, Valinsky W, Miquel P, Montezano AC, Perraud AL, Schmitz C, Shrier A, Touyz RM. (Cell Signal. 2013 Nov;25(11):2163-75. Epub 2013 Jul 6.) Magnesium deficit ? overlooked cause of low vitamin D status? Zittermann A. (BMC Med. 2013 Oct 24;11:229. doi: 10.1186/1741-7015-11-229.) Serum electrolyte levels in relation to macrovascular complications in Chinese patients with diabetes mellitus Wang S, Hou X, Liu Y, Lu H, Wei L, Bao Y, Jia W. (Cardiovasc Diabetol. 2013 Oct 10;12(1):146. doi: 10.1186/1475-2840-12-146.) Magnesium-deficient high-fat diet: Effects on adiposity, lipid profile and insulin sensitivity in growing rats Sales CH, Santos AR, Cintra DE, Colli C. (Clin Nutr. 2013 Oct 16 doi: 10.1016/j.clnu.2013.10.004. Epub ahead of print.) Higher magnesium intake reduces risk of impaired glucose and insulin metabolism, and progression from prediabetes to diabetes in middle-aged Americans Hruby A, Meigs JB, O’Donnell CJ, et al. (Diabetes Care. 2013 Oct 2. Epub ahead of print.) Magnesium homeostasis in cardiac myocytes of Mg-deficient rats Tashiro M, Inoue H, Konishi M. (PLoS One. 2013 Sep 9;8(9):e73171. doi: 10.1371/journal.pone.0073171.) The structure and regulation of magnesium selective ion channels Payandeh J, Pfoh R, Pai EF. (Biochim Biophys Acta. 2013 Nov;1828(11):2778-2792. Epub 2013 Aug 15.) Magnesium, vitamin D status and mortality: results from US National Health and Nutrition Examination Survey (NHANES) 2001 to 2006 and NHANES III Deng X, Song Y, Manson JE et al. (BMC Med. 2013 Aug 27;11(1):187. Epub ahead of print) Phosphoinositide 3-kinase/Akt pathway is involved in mediating the anti-inflammation effects of magnesium sulfate Su NY, Peng TC, Tsai PS, Huang CJ. (J Surg Res. 2013 Jul 4. doi:pii: S0022-4804(13)00660-4. 10.1016/j.jss.2013.06.030. Epub ahead of print) Substitution p.A350V in Na(+)/Mg(2+) Exchanger SLC41A1, Potentially Associated with Parkinson's Disease, Is a Gain-of-Function Mutation Kolisek M, Sponder G, Mastrototaro L, et al. (PLoS One. 2013 Aug 15;8(8):e71096) SLC41A1 is the only magnesium responsive gene significantly overexpressed in placentas of preeclamptic women Kolisek M, Galaviz-Hernández C, Vázquez-Alaniz F, et al. (Hypertens Pregnancy. 2013 Nov;32(4):378-89) Clinical relevance and utility of cetuximab-related changes in magnesium and calcium serum levels Stintzing S, Fischhaber D, Mook C, et al. (Anticancer Drugs. 2013 Oct;24(9):969-74) TRPM7 is required for breast tumor cell metastasis Middelbeek J, Kuipers AJ, Henneman L, et al. (Cancer Res. 2012 Aug 15;72(16):4250-61. Epub 2012 Aug 7.) Mg2+ regulates cytotoxic functions of NK and CD8 T cells in chronic EBV infection through NKG2D Chaigne-Delalande B, Li FY, O’Connor GM, et al. (Science. 2013 Jul 12;341(6142):186-91) TRPM7 mediates breast cancer cell migration and invasion through the MAPK pathway Meng X, Cai C, Wu J, et al. (Cancer Lett. 2013 Jun 1;333(1):96-102. doi: 10.1016/j.canlet.2013.01.031. Epub 2013 Jan 23.) Induction of epithelial-mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent Davis FM, Azimi I, Faville RA, Peters AA et al. (Oncogene. 2013 May 20. doi: 10.1038/onc.2013.187.) Magnesium homeostasis and hypomagnesemia in children with malignancy Kaplinsky C, Alon US. (Pediatr Blood Cancer. 2013 May;60(5):734-40) Association of hypomagnesemia with inferior survival in a phase III, randomized study of cetuximab plus best supportive care versus best supportive care alone: NCIC CTG/AGITG CO.17 Vickers MM, Karapetis CS, Tu D, et al. (Ann Oncol. 2013 Apr;24(4):953-60) Nature of SLC41A1 complexes: report on the split-ubiquitin yeast two hybrid assay Nestler A, Sponder G, Rutschmann K et al. (Magnes Res. 2013 Apr-Jun;26(2):56-66) The SLC41 family of MgtE-like magnesium transporters Sahni J, Scharenberg AM. (PLoS One. 2013 Apr;34(2-3):620-8.) Baseline serum magnesium concentrations and neurodevelopmental outcomes of extremely low birth weight premature infants Kim SY, El-Dib M, Ahmad T, Aly H. (Early Hum Dev. 2013 Apr;89(4):239-42.) Higher Magnesium Intake Is Associated with Lower Fasting Glucose and Insulin, with No Evidence of Interaction with Select Genetic Loci, in a Meta-Analysis of 15 CHARGE Consortium Studies Hruby A, Ngwa JS, Renström F, et al. (J Nutr. 2013 Mar;143(3):345-53.) Sphingosine and FTY720 are potent inhibitors of the transient receptor potential melastatin 7 (TRPM7) channels Qin X, Yue Z, Sun B, et al. (Br J Pharmacol. 2013 Mar;168(6):1294-312.) Magnesium sulphate for women at term for neuroprotection of the fetus Nguyen TM, Crowther CA, Wilkinson D, Bain E. (Cochrane Database Syst Rev. 2013 Feb 28.) Magnesium Supplementation Reduces Postoperative Arrhythmias After Cardiopulmonary Bypass in Pediatrics: A Metaanalysis of Randomized Controlled Trials Lee HY, Ghimire S, Kim EY. (Pediatr Cardiol. 2013 Feb 27.) Safety and efficacy of calcium and magnesium infusions in the chemoprevention of oxaliplatin induced sensory neuropathy in digestive tract cancers: A meta-analysis Xu XT, Dai ZH, Xu Q, et al. (J Dig Dis. 2013 Feb 21.) Modifying effect of calcium/magnesium intake ratio and mortality: a population-based cohort study Dai Q, Shu XO, Deng X, et al (BMJ Open. 2013 Feb 20;3(2)) The TRPM6/EGF Pathway Is Downregulated in a Rat Model of Cisplatin Nephrotoxicity Ledeganck KJ, Boulet GA, Bogers JJ, et al (PLoS One 2013;8(2) Epub 2013 Feb 15.) Associations of serum and urinary magnesium with the pre-diabetes, diabetes and diabetic complications in the chinese northeast population Xu J, Xu W, Yao H, et al. (PLoS One 2013;8(2), Epub 2013 Feb 13.) TRPM7 mediates breast cancer cell migration and invasion through the MAPK pathway Meng X, Cai C, Wu J, et al (Cancer Lett. 2013 Jan 23. Epub ahead of print) Increase in serum Ca2+/Mg2+ ratio promotes proliferation of prostate cancer cells by activating TRPM7 channels Sun Y, Selvaraj S, Varma A et al (J Biol Chem. 2013 Jan 4;288(1):255-63.)